Associate Professor, Pediatrics, Johns Hopkins University School of Medicine.
An endocrinologist, Dr. Wolfe serves as the director of research training in endocrinology in the Division of Pediatric Endocrinology at Johns Hopkins Children’s Center. He also is the director of training in basic science for the Endocrine Diabetes and Metabolism Training Program.
Dr. Wolfe earned his doctoral degree in neuroscience from Northwestern University and completed a research fellowship at Boston Children’s Hospital. Prior to joining the Johns Hopkins faculty in 2007, Dr. Wolfe served as both an assistant professor of pediatrics and Director of Basic Science Research in the University of Chicago’s Division of Pediatric Endocrinology.
His research aims to better understand the regulatory mechanisms of the hypothalamic-pituitary-gonadal axis. Among the body’s most important signaling pathways, this axis controls growth, metabolism and reproduction.
Dr. Wolfe’s work particularly focuses on understanding how the metabolic dysfunction of conditions such as type 2 diabetes, obesity and polycystic ovary syndrome affects reproduction and fertility—as well as the precise signaling pathways that result in those malfunctions.
Some of Dr. Wolfe’s work has yielded valuable new clues about the relationship between insulin sensitivity in the pituitary gland and ovaries and the development of infertility—findings poised to pave the way for new therapies.
Among his honors, Dr. Wolfe was elected in 2013 to the prestigious Society for Pediatric Research for his contributions to the study of childhood disease.