Shel Hwa Yeo

Research Associate, Department of Physiology, Development and Neuroscience, Cambridge University, UK

My research interest is the kisspeptin neuronal network in the adult mouse brain. Kisspeptin neuropeptides are the potent stimulators of the gonadotrophin-releasing hormone (GnRH) neurons that govern the reproductive functions in mammals. My current research aims to map out the afferent inputs onto kisspeptin neurons in the adult female mouse brain. I am also interested in the changes of these neuronal circuits under different physiological conditions such as ovulations, lactation and aging. By using viral transneuronal tracing combined with Cre/loxP recombination technology, I want to map out the synaptic inputs to kisspeptin neurons. The main techniques involved in my research are stereotaxic injection, immunohistochemistry, confocal microscopy and hormonal manipulations.

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