Name: Silvia Leon Tellez
Mentor: Victor Navarro
Academic affiliation: Brigham and Women’s Hospital, Harvard Medical School, Boston, USA
I am a Postdoctoral Research Fellow at the Brigham and Women’s Hospital /Harvard Medical School (USA) in Victor Navarro’s lab. My expertise lies mostly in the study of the functional relevance of the RFRP-3/NPFF1R system in the control of body weight and reproductive maturation/function through the generation and functional characterization of the first NPFF1R KO mouse line. During my PhD I also worked on the characterization of a GPR54KO with rescued GPR54 expression under the GnRH promoter. Currently one of my projects focuses on study of the involvement of tachykinins in the GnRH/LH pulse generation in the mouse. My research experience comprises techniques in molecular biology, such as RNA isolation, RT-PCR, qPCR, RNA ISH, ELISA and in vivo techniques related with animal experimentation, acquired during my pre- & post-doctoral research periods at the Department of Physiology of the University of Cordoba (Spain) under the supervision of Prof. Manuel Tena-Sempere as well as in my current lab in Boston. In addition, during my pre-doctoral period, I stayed for three months at the Division of Neuroscience, Oregon National Primate Research Center (ONPRC)/ Oregon Health & Science University (OHSU) under the supervision of the professor Sergio. R Ojeda. During this stay, I learned a series of molecular techniques that are currently in use at the Ojeda lab to gain insights into the molecular and genetic mechanisms underlying normal and deranged sexual/pubertal development.